Protective effect of wild Corni fructus methanolic extract against acute alcoholic liver injury in mice.
MouseChemical/toxinFemale50, 100 or 200 mg/kg body weight per dayGiven concurrently with alcohol over the three days of dosing
Model: Acute alcohol-induced liver injury, alcohol administered on three consecutive days
The extract significantly reduced serum transaminases and thiobarbituric acid reactive species, inhibited hydroxyl radicals, increased hepatic antioxidant defences and inhibited CYP2E1 expression and activity (p less than 0.05), indicating protection against acute alcohol-induced oxidative liver in…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.