Pequi (Caryocar brasiliense Camb.) almond oil attenuates carbon tetrachloride-induced acute hepatic injury in rats: Antioxidant and anti-inflammatory effects.
RatChemical/toxinWistarmalepequi almond oil 3 or 6 mL/kg; CCl4 3 mL/kg (70%) for induc…pretreatment for 21 days before CCl4 induction
Model: carbon tetrachloride (CCl4)-induced acute hepatic injury
Pretreatment with pequi almond oil at 3 or 6 mL/kg for 21 days before CCl4 induction decreased ALT and AST, reduced hepatic lesions, increased HDL, enhanced hepatic antioxidant enzyme activity and reduced inflammatory mediators compared with CCl4 alone, with the cold-pressed oil showing the greater…
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