Protective Effects of Asiatic Acid Against Spinal Cord Injury-Induced Acute Lung Injury in Rats.
RatSpinal cord injuryUnspecifiedSprague-Dawleyn = 150 rats randomly assigned to five groups30 mg/kg and 75 mg/kg
Model: Spinal cord injury-induced acute lung injury
Asiatic acid at 30 and 75 mg/kg reduced lung wet-to-dry ratio, pulmonary permeability index and histological injury, lowered neutrophil infiltration, myeloperoxidase, cytokines, reactive oxygen species and malondialdehyde, raised superoxide dismutase and catalase, upregulated Nrf2 and downregulated…
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