Effect of High- and Low-Frequency Transcutaneous Electrical Nerve Stimulation on Angiogenesis and Myofibroblast Proliferation in Acute Excisional Wounds in Rat Skin.
RatWoundEPM1-WistarMalen = 90 ratsTranscutaneousPulse duration 200 microseconds, current amplitude 15 mAPostoperatively, on 3 consecutive days
Model: Acute excisional wound on the dorsum created with an 8 mm punch
The low frequency group had significantly more blood vessels than the high frequency group on day 3 (P = .004). The high frequency group had fewer blood vessels than control on days 7 (P = .002) and 14 (P = .034) and fewer myofibroblasts than both low frequency and control on day 3 (P = .004) and t…
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