Piper umbellatum L.: A medicinal plant with gastric-ulcer protective and ulcer healing effects in experimental rodent models.
MouseChemical/toxinMale
Model: Acidified ethanol-induced acute gastric ulcer and acetic acid-induced chronic gastric ulcer in rodents
The extract gave potent gastroprotection in the acidified ethanol acute model and healing of the acetic acid chronic ulcer, with antioxidant, antisecretory and anti-inflammatory mechanisms and restoration of altered cytokine levels, but no in vitro activity against Helicobacter pylori.
Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.