The Beneficial Effects of ETS-GS, a Novel Vitamin E Derivative, on a Rat Model of Crush Injury.
RatCrushLimb / muscle crushWistarMale
Model: Crush injury induced by compression of bilateral hindlimbs for 6 h followed by release of compression
ETS-GS improved seven-day survival, attenuated the rise in malondialdehyde, interleukin-6 and high mobility group box 1, preserved superoxide dismutase, reduced lung damage and lowered reactive oxygen species generation in lung and muscle.
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