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PRECLINICAL PUBLICATION · 2016

Boron promotes streptozotocin-induced diabetic wound healing: roles in cell proliferation and migration, growth factor expression, and inflammation.

Rat / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 27206737 ↗2016Reported benefit

Boron promotes streptozotocin-induced diabetic wound healing: roles in cell proliferation and migration, growth factor expression, and inflammation.

RatWoundWistarTopical hydrogel formulation

Model: Full-thickness excisional skin wound in streptozotocin-induced diabetic rats

Both boron compounds increased dermal cell proliferation, migration and growth factor and gene expression with marked antimicrobial activity, sodium pentaborate pentahydrate being the more active. The sodium pentaborate pentahydrate gel improved wound healing rate and histopathological scores in di…

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.