Protective effect of Mimosa pudica L. in an L-arginine model of acute necrotising pancreatitis in rats.
RatChemical/toxinSprague-DawleyMaleOral400 mg/kg
Model: L-arginine-induced acute necrotising pancreatitis (two intraperitoneal injections of 2 g/kg L-arginine 1 h apart)
MPE reduced severity of acute necrotising pancreatitis, improving diagnostic markers, inflammation and oxidative stress, and promoted pancreatic repair with reduced fibrosis.
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