Nondermal irritating hyperosmotic nanoemulsions reduce treatment times in a contamination model of wound healing.
Guinea pigWoundFemaleTopicalAfter wounding and inoculation
Model: Full-thickness biopsy wound inoculated with Escherichia coli and Enterococcus faecalis at 5 x 10^6 total CFU
HNE reduced bacterial burden by about 3 logs within 24 h and shortened wound closure to 7.6 plus or minus 0.2 days versus 10.2 plus or minus 0.4 days for silver sulfadiazine and 10.4 plus or minus 0.3 days for control.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.