Sleep Modulation Alleviates Axonal Damage and Cognitive Decline after Rodent Traumatic Brain Injury.
RatTBIClosed-head / concussionSprague-DawleyMaleAcutely after trauma
Model: Closed skull traumatic brain injury producing diffuse axonal injury
Both sleep induction and sleep restriction acutely after traumatic brain injury enhanced encephalographic slow-wave activity, markedly reduced diffuse axonal damage in the cortex and hippocampus, and improved memory impairment 2 weeks after trauma, suggesting a disease-modifying effect of enhancing…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.