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PRECLINICAL PUBLICATION · 2016

Low-level laser therapy attenuates the acute inflammatory response induced by muscle traumatic injury.

Rat / Crush

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 26983894 ↗2016Reported benefit

Low-level laser therapy attenuates the acute inflammatory response induced by muscle traumatic injury.

RatCrushLimb / muscle crushWistarTranscutaneous laser irradiation of the injured muscle3 and 5 J/cm2Started 2, 12 or 24 h after trauma

Model: Single-impact blunt trauma to the gastrocnemius muscle

Oxidant markers rose from 2 to 24 h after injury and were prevented by 3 J/cm2 given 2 h after trauma; laser also prevented the interleukin-6 and interleukin-10 changes, restored BDNF and VEGF, and recovered normal locomotion.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.