Application of Allogeneic Fibroblast Cultured on Acellular Amniotic Membrane for Full-thickness Wound Healing in Rats.
RatWoundWistarmaletopical transplantation onto the woundat the time of wounding
Model: Full-thickness excisional wounds created on the dorsum
All transplanted wounds contracted significantly more than non-transplanted wounds. Wounds treated with fibroblast-seeded or plain acellular amniotic membrane showed significantly greater epidermal thickness and improved epidermal healing, and granulation tissue was more organised in the fibroblast…
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