Pharmacological reports about gastroprotective effects of methanolic extract from leaves of Solidago chilensis (Brazilian arnica) and its components quercitrin and afzelin in rodents.
MixedChemical/toxinWistar ratsoral and intraduodenalExtract 100 or 300 mg/kg orally and 100 mg/kg intraduodenal…
Model: Acute gastric ulcer induced by ethanol/HCl in mice and by indomethacin in rats, and chronic gastric ulcer induced by 10 per cent acetic acid in mice
The extract reduced ethanol/HCl-induced ulcer area at 100 and 300 mg/kg, prevented mucus depletion and glutathione loss and limited the rise in myeloperoxidase at 300 mg/kg, reduced indomethacin-induced ulcers at 100 mg/kg and reduced gastric secretion volume and acidity intraduodenally. Quercitrin…
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.