PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2016

Attenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush.

Rat / Crush

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 26732591 ↗2016Reported benefit

Attenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush.

RatCrushPeripheral-nerve crushWistarFemaleGiven around the time of optic nerve crush

Model: Optic nerve crush with in vivo live imaging of axonal degeneration

Calcium channel inhibition attenuated acute axonal degeneration and improved retinal ganglion cell survival and axonal regeneration at 28 days after optic nerve crush.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.