Indenes and tetralenes analogues attenuates lipopolysaccharide-induced inflammation: An in-vitro and in-vivo study.
MouseEndotoxin/LPSBALB/cFemaleOralGiven in the context of LPS challenge; exact timing not stated in the abstract
Model: Lipopolysaccharide induced systemic inflammation and sepsis, with macrophage cultures in vitro
Oral TAF-5 reduced pro-inflammatory cytokines, attenuated organ injury and improved survival after LPS challenge in a dose dependent manner without acute oral toxicity.
Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.