PRECLINICAL PUBLICATION · 2016

Beneficial Effect of Erythropoietin Short Peptide on Acute Traumatic Brain Injury.

Mouse / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

JM4, a 19 amino acid non-haematopoietic erythropoietin derived peptide covering residues 28 to 46

PMID 26715414 ↗2016Reported benefit

Beneficial Effect of Erythropoietin Short Peptide on Acute Traumatic Brain Injury.

MouseTBIControlled cortical impactC57BL/6MaleTreatment window remained open for at least 9 h after injury

Model: Controlled cortical impact traumatic brain injury

JM4 reduced neural cell death and lesion size at 3 and 8 days after controlled cortical impact and improved functional recovery, with efficacy retained when given up to 9 h after injury.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.