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PRECLINICAL PUBLICATION · 2014

Cryotherapy suppresses tendon inflammation in an animal model.

Mouse / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 26594634 ↗2014Reported benefit

Cryotherapy suppresses tendon inflammation in an animal model.

MouseOtherLocal external cold application to patellar and Achilles tendonsImmediately after treadmill running or after needle penetration injury

Model: Exhaustive treadmill running and acute needle penetration injury of patellar and Achilles tendons

Treadmill running raised prostaglandin E2 in patellar and Achilles tendons, and 30 min of cold treatment returned levels to near baseline. Extending treatment to 60 min gave only a marginal further decrease in patellar tendon but a marked decrease in Achilles tendon. COX-2 protein fell with cold tr…

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.