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PRECLINICAL PUBLICATION · 2015

Vagal efferent stimulation protects against Mesobuthus tamulus venom-induced acute respiratory distress syndrome in rats.

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 26525658 ↗2015Mixed findings

Vagal efferent stimulation protects against Mesobuthus tamulus venom-induced acute respiratory distress syndrome in rats.

RatChemical/toxinFemale

Model: Mesobuthus tamulus venom or oleic acid induced acute respiratory distress syndrome in anaesthetised rats

Vagal efferent stimulation prolonged survival time and significantly attenuated all measured parameters of venom-induced ARDS, whereas in the oleic acid model only histopathological changes improved and survival time was not prolonged; GTS-21 pretreatment exacerbated both models.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.