EGb761 improves histological and functional recovery in rats with acute spinal cord contusion injury.
RatSpinal cord injuryContusionSprague-DawleyFemalen = N=30 rats randomised into three groups (sham-operated, sali…Administered during the acute phase after spinal cord injury
Model: Acute standardised spinal cord contusion injury
EGb761-treated rats had significantly better BBB scores at 14 days post injury (P<0.05) but not at 1, 3 or 7 days, together with increased stride length, decreased stride width and less toe dragging at 14 days. Necrosis area was reduced and apoptotic cell numbers were significantly lower at 7 days…
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