PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2015

Beneficial effects of fluid resuscitation via the rectum on hemodynamic disorders and multiple organ injuries in an experimental severe acute pancreatitis model.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 26424226 ↗2015Reported benefit

Beneficial effects of fluid resuscitation via the rectum on hemodynamic disorders and multiple organ injuries in an experimental severe acute pancreatitis model.

RatOtherSprague-DawleyMaleRectal administrationEarly stage of severe acute pancreatitis

Model: Experimental severe acute pancreatitis

Mean arterial pressure rebounded after 6 hours of rectal fluid resuscitation and reached sham levels by the end of treatment, with a fall in haematocrit relative to no resuscitation. Compared with intravenous resuscitation, rectal resuscitation reduced abdominal ascites and lung wet to dry ratio an…

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.