PRECLINICAL PUBLICATION · 2016

Piperine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Modulating NF-kappaB Signaling Pathways.

Mouse / Endotoxin/LPS

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Piperine

PMID 26410851 ↗2016Reported benefit

Piperine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Modulating NF-kappaB Signaling Pathways.

MouseEndotoxin/LPSBALB/cMale

Model: Lipopolysaccharide-induced acute lung injury

Piperine attenuated LPS-induced myeloperoxidase activity, lung oedema and TNF-alpha, IL-6 and IL-1beta production, improved lung histology and significantly inhibited LPS-induced NF-kappaB activation.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.