Inhibition of Lymphangiogenesis and Hemangiogenesis in Corneal Inflammation by Subconjunctival Prox1 siRNA Injection in Rats.
RatChemical/toxinmaleSubconjunctival injection
Model: Alkali burn-induced inflammatory corneal neovascularisation
Subconjunctival Prox1 siRNA significantly inhibited alkali burn-induced corneal lymphangiogenesis and haemangiogenesis compared with scrambled siRNA, to an extent comparable with bevacizumab, and also reduced macrophage and leukocyte infiltration and downregulated LYVE-1, podoplanin, VEGFR2 and VEG…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.