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PRECLINICAL PUBLICATION · 2015

Treatment of Acute Vocal Fold Injury With Platelet-Rich Plasma.

Rat / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 26292799 ↗2015Mixed findings

Treatment of Acute Vocal Fold Injury With Platelet-Rich Plasma.

RatWoundWistarMalen = 24 Wistar rats in total, 10 animals unilaterally injured an…Topical application to the injured vocal fold on gelfoamApplied immediately after injury

Model: Unilateral acute vocal fold injury created with a microscissor through the entire lamina propria down to the thyroarytenoid muscle

Collagen and VEGF were higher in the platelet-rich plasma group but the difference from control was not statistically significant, and lymphocyte counts did not differ between groups. EGFR and FGFR1 were significantly higher in the treated group (p < 0.05), which the authors interpret as accelerate…

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.