Ginsenoside Rg3 attenuated omethoate-induced lung injury in rats.
RatChemical/toxinSprague-DawleyMale5, 10 or 20 mg/kgAdministered after subcutaneous omethoate exposure
Model: Acute omethoate (organophosphate) poisoning induced lung injury, omethoate given subcutaneously as a single 60 mg/kg dose
Ginsenoside Rg3 attenuated omethoate-induced lung injury, increasing lung glutathione (p less than 0.05 or p less than 0.01), ameliorating the altered activities of superoxide dismutase and catalase (p less than 0.05 or p less than 0.01) and significantly reducing malondialdehyde, TNF-alpha and mye…
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