Effects of lipo-prostaglandin E1 on wound bed microcirculation.
RatWoundWistarMaleInjection (specific route not stated in the abstract)Medium dose 6 microgram/2 ml/kg; high dose 10 microgram/2 m…Administered after creation of the ear skin wound bed, with acute stimulation a…
Model: Microsurgical excision of the superficial stratum of the ear skin preserving the subdermal vascular plexus, creating a wound bed for intravital visualisation of microcirculation
Wound bed blood flow increased significantly 10 minutes after lipo-PGE1 injection (p<0.05), approximately fourfold above baseline, with the greatest increase in the medium-dose group; extravasation and accumulation of lipo-PGE1 in the wound bed were observed
Extraction: extract · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.