PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2015

Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice.

Mouse / Ischaemia-reperfusion

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 26198166 ↗2015Reported benefit

Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice.

MouseIschaemia-reperfusionRenalSCID (immunodeficient)MaleRenal subcapsular transplantation

Model: Acute kidney injury induced by renal ischaemia/reperfusion injury

Renal subcapsular transplantation of hiPSC-derived renal progenitors ameliorated ischaemia/reperfusion-induced acute kidney injury, significantly suppressing elevations in blood urea nitrogen and serum creatinine and attenuating histopathological changes including tubular necrosis, tubule dilatatio…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.