Evaluation of anti-inflammatory activity of the methanolic extract from Jungia rugosa leaves in rodents.
MixedChemical/toxinWistar rats; mouse strain not statedMaleIntraperitoneal125, 250 and 500 mg/kg
Model: Croton oil-induced ear oedema in mice, carrageenan-induced paw oedema in rats, and cotton pellet-induced granuloma in mice as a model of chronic inflammation
Intraperitoneal JRLE at 125, 250 and 500 mg/kg significantly inhibited croton oil-induced ear oedema and myeloperoxidase activity in mice (p<0.01-0.001); carrageenan-induced paw oedema in rats was significantly reduced only at 500 mg/kg (p<0.05); granuloma formation was reduced by 11.7% (125 mg/kg)…
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.