The effect of electroacupuncture at ST36 on severe thermal injury-induced remote acute lung injury in rats.
RatBurnScaldSprague-DawleyMalen = 40 male rats randomly divided into five groupsElectroacupuncture applied at the ST36 acupoint (or at a non-acupoint in the control arm)Electroacupuncture stimulation parameters 3 V, 2 ms, 3 Hz;…Electroacupuncture applied after the 30% total body surface area scald; alpha-b…
Model: Severe thermal injury by third-degree scald over 30% of total body surface area, with remote acute lung injury as the readout
Thermal injury of 30% total body surface area induced alveolar leukocytosis, interstitial oedema and increases in interleukin-1beta, interleukin-6 and HMGB-1, with significantly enhanced HMGB-1 messenger RNA and protein expression in lung tissue. Electroacupuncture at ST36 significantly downregulat…
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