Coadministration of the Human Umbilical Cord Matrix-Derived Mesenchymal Cells and Aspirin Alters Postischemic Brain Injury in Rats.
RatIschaemia-reperfusionCerebral (MCAO/stroke)Sprague-DawleyMale
Model: Transient middle cerebral artery occlusion (focal cerebral ischaemia)
Aspirin and human umbilical cord matrix-derived mesenchymal cells each significantly improved learning and memory recovery and reduced the ischaemic area compared with untreated ischaemic rats; coadministration gave no additional benefit over either treatment alone.
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