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PRECLINICAL PUBLICATION · 2015

Treatment with a neutralising anti-rat interleukin-17 antibody after multiple-trauma reduces lung inflammation.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 26100210 ↗2015Reported benefit

Treatment with a neutralising anti-rat interleukin-17 antibody after multiple-trauma reduces lung inflammation.

RatOtherSprague-DawleyFemaleAfter the multiple-trauma model was established

Model: Multiple trauma (polytrauma) model in rats

Neutralisation of interleukin 17 lowered serum interleukin 17 and lung interleukin 17 mRNA and reduced lung tissue inflammation after multiple trauma. No quantitative magnitudes were reported in the abstract.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.