The effects of porcine pulmonary surfactant on smoke inhalation injury.
RatOtherSprague-DawleyMalen = 15 rats in three groups of 5Instilled into the airway
Model: Smoke inhalation injury in rats
Surfactant instillation increased arterial oxygen tension, improved oedema status, decreased vascular permeability, improved lung histopathology and reduced the inflammatory response, and increased endogenous surfactant protein A, which correlated negatively with myeloperoxidase activity and interl…
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