Honey feeding protects kidney against cisplatin nephrotoxicity through suppression of inflammation.
MouseChemical/toxinC57BL/6MaleOral (feeding)Oral pre-treatment for one week before cisplatin, continued for a further 3 day…
Model: Cisplatin-induced nephrotoxicity (acute kidney injury)
Honey-fed animals had less cisplatin-induced kidney dysfunction with lower serum creatinine, better preserved kidney morphology, significantly reduced tubular epithelial cell death, less immune infiltration, lower cytokine and chemokine expression and complete suppression of the cisplatin-induced i…
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