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PRECLINICAL PUBLICATION · 2015

The secretome of apoptotic human peripheral blood mononuclear cells attenuates secondary damage following spinal cord injury in rats.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25797576 ↗2015Reported benefit

The secretome of apoptotic human peripheral blood mononuclear cells attenuates secondary damage following spinal cord injury in rats.

RatSpinal cord injuryContusionSprague-DawleyMaleSystemic

Model: Spinal cord contusion injury

MNC-secretome improved functional recovery, reduced cavity formation and acute axonal injury, increased vascular density and CD68 recruitment, and lowered inducible nitric oxide synthase expression compared with controls.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.