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PRECLINICAL PUBLICATION · 2015

Serum Glial Fibrillary Acidic Protein Predicts Tissue Glial Fibrillary Acidic Protein Break-Down Products and Therapeutic Efficacy after Penetrating Ballistic-Like Brain Injury.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25789543 ↗2015Reported benefit

Serum Glial Fibrillary Acidic Protein Predicts Tissue Glial Fibrillary Acidic Protein Break-Down Products and Therapeutic Efficacy after Penetrating Ballistic-Like Brain Injury.

RatTBIPenetrating / ballisticSprague-DawleyMale2.5 mg/kgAfter injury

Model: Penetrating ballistic-like brain injury

Cyclosporin A at 2.5 mg/kg reduced the 2 h post-injury serum glial fibrillary acidic protein elevation 22.4-fold relative to injury plus vehicle (p<0.05) and improved neurological function at 1 day after injury.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.