Protective effects of Acanthopanax vs. Ulinastatin against severe acute pancreatitis-induced brain injury in rats.
RatOtherSprague-DawleyMale
Model: Surgically induced severe acute pancreatitis with secondary brain injury; sham operation as negative control
Both acanthopanax and ulinastatin lowered mortality, pro-inflammatory cytokines, NF-kappaB p65 activity and pancreatic and brain pathology scores relative to the untreated model, with no significant difference between the two treatments.
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