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PRECLINICAL PUBLICATION · 2014

Prophylactic inhalation of L-alanyl-L-glutamine enhances heat shock protein 72 and attenuates endotoxin-induced lung injury in rats.

Rat / Endotoxin/LPS

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25470514 ↗2014Reported benefit

Prophylactic inhalation of L-alanyl-L-glutamine enhances heat shock protein 72 and attenuates endotoxin-induced lung injury in rats.

RatEndotoxin/LPSSprague-DawleyMaleInhalationProphylactic, 12 hours before lipopolysaccharide inhalation

Model: Acute lung injury induced by lipopolysaccharide inhalation

Glutamine inhalation increased lung HSP72 and, when given 12 hours before lipopolysaccharide, reduced lung injury score, lavage lactate dehydrogenase activity and neutrophil percentage.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.