PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2014

The radical scavenger edaravone improves neurologic function and perihematomal glucose metabolism after acute intracerebral hemorrhage.

Rat / Haemorrhage/shock

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25440340 ↗2014Reported benefit

The radical scavenger edaravone improves neurologic function and perihematomal glucose metabolism after acute intracerebral hemorrhage.

RatHaemorrhage/shockUnspecifiedSprague-DawleyMaleAfter blood infusion

Model: Autologous blood infusion model of intracerebral haemorrhage

Edaravone improved forelimb placing and corner turn performance, reduced brain water content at day 3, increased the perihaematomal lesion-to-normal FDG uptake ratio, reduced injury volume and decreased apoptotic cell numbers.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.