Hepatoprotective effect of ethanol extract from Berchemia lineate against CCl4-induced acute hepatotoxicity in mice.
MouseChemical/toxinMaleIntragastric100, 200 and 400 mg/kgAdministered for 7 consecutive days
Model: Carbon tetrachloride induced acute liver injury
BELE at 400 mg/kg significantly decreased serum ALT (56.25 U/L), AST (297.67 U/L), ALP (188.20 U/L) and total bilirubin (17.90 mol/L) and raised total protein (64.67 g/L), with dose-dependent increases in SOD (291.17, 310.32 and 325.67 U/mg protein) and reductions in MDA (7.27, 6.77 and 5.33 nmol/m…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.