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PRECLINICAL PUBLICATION · 2014

Application of adipose tissue-derived stem cells in a rat rotator cuff repair model.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25384471 ↗2014Mixed findings

Application of adipose tissue-derived stem cells in a rat rotator cuff repair model.

RatOtherSprague-Dawleyn = 50 Sprague-Dawley rats in total, 32 for biomechanical study…Local application on a collagen carrier at the repair site2 x 10^6 ASCsAt the time of tendon detachment and repair surgery

Model: Surgical detachment and repair of the supraspinatus tendon (rotator cuff repair model)

Adipose-derived stem cells did not improve the biomechanical properties of tendon-to-bone healing at 2 or 4 weeks but were associated with less acute inflammation and reduced oedema and neutrophil presence.

Extraction: extract · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.