Wound healing after thermal injury is improved by fat and adipose-derived stem cell isografts.
MouseBurnScaldC57BL/6Malen = 20 mice in total, 5 per group across four groupsSubcutaneous injection at the burn site500 microlitres of processed adipose, adipose-derived stem…First day after injury
Model: 30% total body surface area partial-thickness scald burn by exposure to 60 degrees Celsius water for 17 seconds
All treated groups showed decreased wound depth and area and reduced apoptotic activity compared with untreated burns. Groups containing adipose-derived stem cells showed a non-significant increase in vascularity at day 5 and no change in proliferation.
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