Gelsolin: role of a functional protein in mitigating radiation injury.
MouseRadiationMaleAdministration to irradiated mice (route not stated)After radiation exposure
Model: Acute high-dose whole-body caesium-137 gamma irradiation; parallel in vitro irradiation of human intestinal epithelial cells
Irradiation lowered plasma gelsolin and raised cytoplasmic gelsolin dose dependently. Recombinant human plasma gelsolin improved prothrombin time and activated partial thromboplastin time, raised glutathione and lowered malondialdehyde, indicating improved antioxidant status.
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.