The vagus nerve alters the pulmonary dendritic cell response to injury.
MouseBurnUnspecifiedC57BL/6MaleElectrical stimulation of the right cervical vagus nerve
Model: 30% total body surface area steam burn causing acute lung injury
Severe burn increased pulmonary dendritic cell recruitment at 4 h that persisted to 24 h, with no change in pulmonary macrophages. Vagal nerve stimulation limited this dendritic cell recruitment, prevented histological lung injury and attenuated lung interleukin 6 and transforming growth factor bet…
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