Role and mechanism of radiological protection cream in treating radiation dermatitis in rats.
RatRadiationSprague-DawleyMalen = 48 male Sprague-Dawley rats randomised across 4 groupsTopical
Model: Acute radiation dermatitis induced by electron linear accelerator irradiation of the buttock skin
Rp protected cellular and subcellular skin structures after irradiation and promoted collagen fibre proliferation and restoration. Ku70/80 mRNA was higher in the Rp and trolamine cream groups than the model group (P less than 0.05). Efficiency in reducing grade III and IV dermatitis was 85.7% for R…
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