beta(2)-Adrenoreceptor blockade improves early posttrauma hyperglycemia and pulmonary injury in obese rats.
RatOtherobese Zucker and lean Zuckermaleintravenous0.2 mg/kg/hDuring the 6 h posttrauma monitoring period; exact start time relative to traum…
Model: Orthopaedic trauma applied to both hindlimbs
Trauma induced rapid hepatic glycogenolysis with reduced liver glycogen, which was inhibited by ICI-118551. Obese Zucker rats showed higher posttrauma glucose, IL-6, lung neutrophil infiltration and myeloperoxidase activity than lean Zucker rats, and an increased lung wet-to-dry weight ratio not se…
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