Reducing the histopathological changes of radioiodine to the lacrimal glands by a popular anti-oxidant: lycopene.
RatRadiationWistarn = 32 rats: control n=8, radioiodine n=12, lycopene n=12Oral by gastric gavage1 cc lycopeneGiven with the radioiodine dose
Model: Acute lacrimal gland injury after a single 3 mCi dose of radioiodine (131I) given by gastric gavage
Cell shape and size variation and poorly defined acidophilic cell outlines were significantly less frequent in the lycopene group than in the radioiodine group.
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