An autologously generated platelet-rich plasma suturable membrane may enhance peripheral nerve regeneration after neurorraphy in an acute injury model of sciatic nerve neurotmesis.
RatOtherWistarn = 36 rats, 32 operated and split into two groups, 4 uninjured…Local application around the neurorrhaphy siteAt the time of nerve repair surgery
Model: Sciatic nerve neurotmesis followed by neurorrhaphy
Treated nerves showed higher fibre density at 6 weeks and larger fibre diameters at 12 weeks with significant effects on electromyographic parameters at both time points.
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