Cardioprotective effects of phosphocreatine on myocardial cell ultrastructure and calcium-sensing receptor expression in the acute period following high level spinal cord injury.
RatSpinal cord injuryContusionSprague-Dawleymalen = 54 rats, 6 per group per time point, plus 6 sham controlsAbdominal (intraperitoneal) injection200 mg/kgAt 6, 12, 24 or 48 h after injury
Model: C7 spinal cord injury by Allen's weight-drop method
Phosphocreatine reduced myocardial ultrastructural damage and lowered calcium-sensing receptor, cardiac troponin I, creatine kinase and CK-MB levels at all time points.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.