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PRECLINICAL PUBLICATION · 2014

The Protective Effect of Stauntonia Chinensis Polysaccharide on CCl4-induced Acute Liver Injuries in Mice.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24711744 ↗2014Reported benefit

The Protective Effect of Stauntonia Chinensis Polysaccharide on CCl4-induced Acute Liver Injuries in Mice.

MouseChemical/toxinKunmingn = 50 mice in total, 10 per group across five groupsOral50, 100 and 200 mg/kg (low, medium and high dose groups)Pre-treatment for 7 days before CCl4 challenge

Model: Carbon tetrachloride (0.15 per cent CCl4 in mixed edible oil, intraperitoneal) acute liver injury

SCP significantly reduced serum alanine transaminase activity, preserved antioxidant defences and lessened histopathological damage to liver tissue after CCl4 challenge.

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.