The mesenchymal stem cell-derived microvesicles enhance sciatic nerve regeneration in rat: a novel approach in peripheral nerve cell therapy.
RatOtherWistarMaleLocal application at the nerve repair siteAt the time of nerve transection and conduit placement
Model: Sciatic nerve transection with a 10 mm gap bridged by a chitosan conduit
Resting and anti-inflammatory mesenchymal stem cell-derived microvesicles produced marked improvement in functional, electrophysiological, muscle mass, histomorphometric and immunohistochemical indices of sciatic nerve regeneration compared with proinflammatory microvesicles.
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.