A novel small-molecule tumor necrosis factor alpha inhibitor attenuates inflammation in a hepatitis mouse model.
MouseChemical/toxinBALB/c
Model: Murine acute hepatitis model (TNF-alpha-mediated liver injury)
C87 attenuated TNF-alpha-induced inflammation in a murine acute hepatitis model, markedly reducing liver injury and improving animal survival. Quantitative in vivo dosing detail was not available because the PMC record returned an empty full text field.
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